Genetic mouse models for skin research: Strategies and resources

I-54: New Models for Human and Mouse Genetic

The possibility to reprogram somatic human cells will greatly and deeply change genetic approach and allow the development of new tools to study genetics diseases. Indeed, our ability to study human genetic diseases suffers from the lack of valid in vitro models. The latter should (i) be originating from human primary cells, (ii) be able to self-renew for a long time and (iii) be able to differ...

Genetic Mouse Models for Osteoarthritis Research

phylogeography and genetic diversity of the lesser mouse- eared bat (myotis blythii) in iran

in current study, 63 samples of bat populations collected from differ regions were used for evaluating the geographic variations. twenty cranial and dental characters for traditional morphometric and landmarks method on the ventral, dorsal skull and mandible for geometry morphometric studies were used. statistical analyses of traditional morphometric and geometry morphometric data indicated low...

Mouse Model Resources for Vision Research

The need for mouse models, with their well-developed genetics and similarity to human physiology and anatomy, is clear and their central role in furthering our understanding of human disease is readily apparent in the literature. Mice carrying mutations that alter developmental pathways or cellular function provide model systems for analyzing defects in comparable human disorders and for testin...

Avian genetic resources for biological research

Research with a variety of genetic stocks has produced many important discoveries in the areas of genetics, virology, immunology, developmental biology, and animal agriculture. (see CRAWFORD 1990, for a review). These include the pioneering studies on Mendelian inheritance and sex determination of BATESON (1902), and BATESON and PUNNETT (1906, 1908). Not surprisingly, given its history of use i...